Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

This OA-based FS model reproduced the key pathological and imaging features of human chronic AP and implicated NETs in the disease progression. It provides a robust platform for mechanistic investigation and therapeutic development.

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Publication Details

Journal
Animal Models and Experimental Medicine
Published
2026-03-24
DOI
https://doi.org/10.1002/ame2.70197
Primary Topic
Dysphagia Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine
Dysphagia Assessment and Management
article

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

article en

Abstract

This OA-based FS model reproduced the key pathological and imaging features of human chronic AP and implicated NETs in the disease progression. It provides a robust platform for mechanistic investigation and therapeutic development.

Animal Models and Experimental Medicine
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Fujian Provincial Hospital (CN), Nanjing Medical University (CN)
Zero hunger
Openalex Percentile: Top 10%
Dysphagia Assessment and Management
DOIOpen Access PDFOpenAlex
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