Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

Men with KS demonstrate increased lectin complement pathway activation capacity, increased MAP-1 and MASP1-201 expression. Altered immune function could be a specific characteristic of KS contributing to the comorbidity burden.

Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2026-03-23
DOI
https://doi.org/10.1210/clinem/dgag129
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

The Journal of Clinical Endocrinology & Metabolism
Complement system in diseases
article

Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome

article en

Abstract

Men with KS demonstrate increased lectin complement pathway activation capacity, increased MAP-1 and MASP1-201 expression. Altered immune function could be a specific characteristic of KS contributing to the comorbidity burden.

The Journal of Clinical Endocrinology & Metabolism
Openalex Percentile: Top 11%
Complement system in diseases
DOIOpen Access PDFOpenAlex
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Increased MAP-1 and lectin complement activation capacity in Klinefelter syndrome · The Journal of Clinical Endocrinology & Metabolism (2026) | TGRS Research Map | TGRS