Caloric restriction attenuates age-related liver and kidney alterations in mice: Histological evidence.
Long-term CR preserves hepatic and renal histoarchitecture during aging by limiting metabolic overload, fibrotic remodeling, and senescence, accompanied by a sustained SIRT1/acetyl-p53 profile consistent with reduced p53 activation.
Authors
- Carlos R. Montes-de-Oca-Saucedo (ORCID: https://orcid.org/0000-0002-2355-2217)
- SHEILA ADELA VILLA-CEDILLO
- Cristina Sarahi Ríos-Vazquez
- Adolfo Soto-Domínguez
- Odila Saucedo-Cárdenas
- Ricardo Ruiz-Salazar
- Mario Murguía-Pérez
- Eduardo Agustín-Godínez
- Eduardo A Álvarez-Tostado-Ojeda
Institutions
- Universidad de Guanajuato (MX)
- Universidad Autónoma de Nuevo León (MX)
- Instituto Tecnológico de León (MX)
Publication Details
- Journal
- PubMed
- Published
- 2026-03-24
- DOI
- https://doi.org/10.14670/hh-25-065
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00