Prognostic value of dynamic sST2 and immune-coagulation biomarkers in severe community-acquired pneumonia: insights from a prospective cohort study

sST2 dynamics significantly enhance CAP risk stratification. The discharge-phase biomarker model outperforms conventional scores,a model using D-dimer, procalcitonin, and lymphocyte percentage is a practical alternative. Integrating recovery-phase biomarkers into discharge planning offers a precision medicine strategy to optimize post-discharge management and reduce adverse outcomes.

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Publication Details

Journal
Expert Review of Molecular Diagnostics
Published
2026-03-24
DOI
https://doi.org/10.1080/14737159.2026.2651164
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic value of dynamic sST2 and immune-coagulation biomarkers in severe community-acquired pneumonia: insights from a prospective cohort study

Jian Dong, Wenjuan Li, Jia Hao Wu
Expert Review of Molecular Diagnostics
IL-33, ST2, and ILC Pathways
article

Prognostic value of dynamic sST2 and immune-coagulation biomarkers in severe community-acquired pneumonia: insights from a prospective cohort study

Jian Dong, Wenjuan Li, Jia Hao Wu
article en

Abstract

sST2 dynamics significantly enhance CAP risk stratification. The discharge-phase biomarker model outperforms conventional scores,a model using D-dimer, procalcitonin, and lymphocyte percentage is a practical alternative. Integrating recovery-phase biomarkers into discharge planning offers a precision medicine strategy to optimize post-discharge management and reduce adverse outcomes.

Expert Review of Molecular Diagnostics
Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 11%
IL-33, ST2, and ILC Pathways
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