Primary pure small cell neuroendocrine carcinoma of the endometrium: a case report

Primary pure small cell neuroendocrine carcinoma of the endometrium is an exceptionally rare and highly malignant neoplasm associated with an unfavorable prognosis. Accurate diagnosis relies on histopathological and immunohistochemical evaluation. In this single-case observation, comprehensive surgical staging followed by platinum-based chemotherapy was administered. However, owing to the limited follow-up duration and the absence of adjuvant radiotherapy, definitive conclusions regarding treatment efficacy cannot be drawn. Larger case series and longer-term follow-up are required to establish optimal management strategies for this rare tumor.