Hepatic histoplasmosis presenting as portal hypertension in an immunocompetent elderly male: A multidisciplinary case report

Histoplasmosis, caused by <i>Histoplasma capsulatum</i>, is a dimorphic fungus typically endemic to parts of the Americas, Africa, and Asia. Inhalational exposure leads primarily to pulmonary infection, and extrapulmonary or isolated hepatic presentations are rare, particularly in immuno-competent individuals. We present an unusual case of hepatic histoplasmosis with no evident lung involvement, highlighting a diagnostic challenge and a rewarding pathologic discovery.

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Publication Details

Journal
Tropical Doctor
Published
2026-03-23
DOI
https://doi.org/10.1177/00494755261435267
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
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article

Hepatic histoplasmosis presenting as portal hypertension in an immunocompetent elderly male: A multidisciplinary case report

Divya Jyoti, Priti Singh, LH Ghotekar
Tropical Doctor
Fungal Infections and Studies
article

Hepatic histoplasmosis presenting as portal hypertension in an immunocompetent elderly male: A multidisciplinary case report

Divya Jyoti, Priti Singh, LH Ghotekar
article en

Abstract

Histoplasmosis, caused by <i>Histoplasma capsulatum</i>, is a dimorphic fungus typically endemic to parts of the Americas, Africa, and Asia. Inhalational exposure leads primarily to pulmonary infection, and extrapulmonary or isolated hepatic presentations are rare, particularly in immuno-competent individuals. We present an unusual case of hepatic histoplasmosis with no evident lung involvement, highlighting a diagnostic challenge and a rewarding pathologic discovery.

Tropical Doctor
Lady Hardinge Medical College (IN)
Good health and well-being
Openalex Percentile: Top 14%
Fungal Infections and Studies
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