Naïve Edible PVLNs: Emerging Versatile Biomaterial in Clinical Strategy

Naïve edible plant vesicle‐like nanoparticles (PVLNs) could be acted as innovative therapeutic strategies due to their versatile role, such as antitumor, antiaging, anti‐inflammation, and drug delivery. The advantages of edible PVLNs have displayed notable benefits including low toxicity, minimal side effects, nonimmunogenicity, and cost‐effective scalability for large‐scale production. In this review, we systematically summarize the methods including the extraction, isolation, and characterization of PVLNs; demonstrate a variety of bioactive components; and evaluate the application potential in disease treatment. PVLNs present promising potential as safe, sustainable, and multifunctional delivery systems for future applications in clinics and health.