Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity

Results of this cohort study reveal that a reduction in BMI z score of at least 0.25 was associated with similar risk reductions for both MHO and MUO. Children with MHO face a substantially increased cardiometabolic disease risk already as young adults compared with the general population. Hence, obesity treatment should be recommended for all children with obesity, regardless of initial metabolic status.

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Publication Details

Journal
JAMA Pediatrics
Published
2026-03-23
DOI
https://doi.org/10.1001/jamapediatrics.2026.0343
Primary Topic
Obesity, Physical Activity, Diet
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity

Emilia Hagman, Pernilla Danielsson, Resthie Rachmanta Putri, Claude Marcus
JAMA Pediatrics
Obesity, Physical Activity, Diet
article

Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity

Emilia Hagman, Pernilla Danielsson, Resthie Rachmanta Putri, Claude Marcus
article en

Abstract

Results of this cohort study reveal that a reduction in BMI z score of at least 0.25 was associated with similar risk reductions for both MHO and MUO. Children with MHO face a substantially increased cardiometabolic disease risk already as young adults compared with the general population. Hence, obesity treatment should be recommended for all children with obesity, regardless of initial metabolic status.

JAMA Pediatrics
Karolinska Institutet (SE)
Openalex Percentile: Top 14%
Obesity, Physical Activity, Diet
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