Cost-utility and budget impact analyses of significant fibrosis detection in individuals with metabolic syndrome or obesity in Thailand
One-time screening was not uniformly cost-effective. In metabolic syndrome, only FIB-4 + TE was cost-effective. In obesity, all strategies were cost-effective. Given non-robustness in the estimated cost-effectiveness and the substantial budget impact, implementation should balance expected health gains against affordability.
Authors
- Pichaya Tantiyavarong (ORCID: https://orcid.org/0000-0003-0793-794X)
- Chayanis Kositamongkol (ORCID: https://orcid.org/0000-0001-7182-0733)
- Pochamana Phisalprapa (ORCID: https://orcid.org/0000-0003-1995-4405)
- Surasak Saokaew (ORCID: https://orcid.org/0000-0002-1382-0660)
- Prawat Kositamongkol (ORCID: https://orcid.org/0000-0002-8797-9658)
- Prawej Mahawithitwong (ORCID: https://orcid.org/0000-0001-9151-8929)
- Alissa Ratanatawan
- Pimsiri Sripongpun
Institutions
- Thammasat University (TH)
- Prince of Songkla University (TH)
- Siriraj Hospital (TH)
- Chulalongkorn University (TH)
- Mahidol University (TH)
- University of Phayao (TH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1371/journal.pone.0344985
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00