Advances in the Different Synthetic Routes of Fluorinated Hydrazines

Hydrazine derivatives are widely used in various research fields, including pharmaceuticals, agrochemicals, polymers, and industrial dyes, as well as serving as precursors in organic synthesis. Given the importance of this scaffold and the growing interest in fluorine's ability to confer specific properties on molecules, the synthesis of fluorinated hydrazines has attracted considerable attention from researchers. This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N-fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.

Authors

Institutions

Publication Details

Journal
The Chemical Record
Published
2026-03-23
DOI
https://doi.org/10.1002/tcr.202500349
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

Dimitra Kyrko, Benoit Crousse
The Chemical Record
Fluorine in Organic Chemistry
article

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

Dimitra Kyrko, Benoit Crousse
article en

Abstract

Hydrazine derivatives are widely used in various research fields, including pharmaceuticals, agrochemicals, polymers, and industrial dyes, as well as serving as precursors in organic synthesis. Given the importance of this scaffold and the growing interest in fluorine's ability to confer specific properties on molecules, the synthesis of fluorinated hydrazines has attracted considerable attention from researchers. This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N-fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.

The Chemical Record
Centre National de la Recherche Scientifique (FR), Université Paris-Saclay (FR)
Openalex Percentile: Top 10%
Fluorine in Organic Chemistry
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.