Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis
Serum conjugated primary BAs accumulate in AH. Elevated HGF may detrimentally affect the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis, contributing to the AH BA profile.
Authors
- Alastair M. Kilpatrick (ORCID: https://orcid.org/0000-0002-4795-8799)
- Mark R. Thursz (ORCID: https://orcid.org/0000-0002-8218-192X)
- Elaine Holmes (ORCID: https://orcid.org/0000-0002-0556-8389)
- Steven Masson (ORCID: https://orcid.org/0000-0003-1041-9844)
- S Ryder
- Nikhil Vergis (ORCID: https://orcid.org/0000-0002-4157-6757)
- Luke D. Tyson (ORCID: https://orcid.org/0000-0003-2745-0282)
- Daniel Rodrigo‐Torres (ORCID: https://orcid.org/0000-0001-7840-1523)
- João Pedro Nunes (ORCID: https://orcid.org/0000-0002-0164-249X)
- Vruti Patel
- Katie Chappell
- Prof Ewan Forrest
- S. A. Forbes
- B Mullish
- Michael Allison
- Paul Richardson
- Andrew Austin
- Laura Martinez‐Gili
- Stephen Atkinson
- Mark J. W. McPhail
- Alexandros Pechlivanis
- Tong Liu
- Mark Wright
Institutions
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- University of Liverpool (GB)
- Imperial College Healthcare NHS Trust (GB)
- King's College - North Carolina (US)
- Royal Derby Hospital (GB)
- Glasgow Royal Infirmary (GB)
- Royal Liverpool University Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- Foundation for Liver Research (GB)
- MRC Centre for Regenerative Medicine (GB)
- St Mary's Hospital (GB)
- NIHR Newcastle Biomedical Research Centre (GB)
- Queen's Medical Centre (GB)
- Nottingham Biomedical Research Centre (GB)
- King's College Hospital (GB)
- Addenbrooke's Hospital (GB)
- Meso Scale Discovery (United States) (US)
- Imperial College London (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1111/apt.70616
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00