Enantioselective Construction of Chiral Quinoline Scaffold via a Michael Addition/O-Alkylation Sequence
An enantioselective Michael/O-alkylation cascade between hydroxyquinolines and chloronitroalkenes was developed, constructing chiral dihydrofuroquinoline scaffolds in high enantioselectivity under mild conditions. The direct modification of hydroxylcamptothecin and the discovery of anti-tumour...
Authors
- Xiaoze Bao (ORCID: https://orcid.org/0000-0003-3682-2674)
- Damien Bonne (ORCID: https://orcid.org/0000-0003-4479-4626)
- Guishun Bai
- Juelian Wang
- Yi Hua
- Yihuan Yang
- Jian-Wei Chen
- Yue Wei
- Hong Wang
Publication Details
- Journal
- Chemical Communications
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d6cc00882h
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00