Modulation of oxidation-related immune markers by lipid-lowering medications in individuals with elevated lipoprotein(a)

In individuals with Lp(a) levels ≥ 75 nmol/L, high-intensity statins, add-on ezetimibe and add-on PCSK9i reduced IgG apoB-IC but did not affect IgM apoB-IC, or IgG and IgM anti-MDA-mimotope levels. The clinical significance of these findings warrants further investigation.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2026-03-23
DOI
https://doi.org/10.1007/s00392-026-02896-5
Primary Topic
Atherosclerosis and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
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article

Modulation of oxidation-related immune markers by lipid-lowering medications in individuals with elevated lipoprotein(a)

Amalia Despoina Koutsogianni, GEORGE LIAMIS, Constantinos C. Tellis, Sotirios Tsimikas et al.
Clinical Research in Cardiology
Atherosclerosis and Cardiovascular Diseases
article

Modulation of oxidation-related immune markers by lipid-lowering medications in individuals with elevated lipoprotein(a)

Amalia Despoina Koutsogianni, GEORGE LIAMIS, Constantinos C. Tellis, Sotirios Tsimikas, Alexandros Tselepis, Evangelos Liberopoulos, Fotios Barkas
article en

Abstract

In individuals with Lp(a) levels ≥ 75 nmol/L, high-intensity statins, add-on ezetimibe and add-on PCSK9i reduced IgG apoB-IC but did not affect IgM apoB-IC, or IgG and IgM anti-MDA-mimotope levels. The clinical significance of these findings warrants further investigation.

Clinical Research in Cardiology
University of Ioannina (GR), University of California San Diego (US), Laiko General Hospital of Athens (GR)
Good health and well-being
Openalex Percentile: Top 11%
Atherosclerosis and Cardiovascular Diseases
DOIOpen Access PDFOpenAlex
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Modulation of oxidation-related immune markers by lipid-lowering medications in individuals with elevated lipoprotein(a) — Amalia Despoina Koutsogianni, GEORGE LIAMIS, et al. · Clinical Research in Cardiology (2026) | TGRS Research Map | TGRS