Mast cell activation within the mesentery depends on vagal signaling following abdominal surgery

Introduction: Abdominal surgery causes an inflammatory reaction in the intestines, resulting in a postoperative ileus.Mast cells can be divided into mucosal mast cells and connective tissue mast cells.In this study, we investigated mast cell activation within the gastrointestinal tract during abdominal surgery and explored the activation and role of connective tissue mast cells in postoperative ileus.

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Publication Details

Journal
Surgery Open Science
Published
2026-03-23
DOI
https://doi.org/10.1016/j.sopen.2026.03.005
Primary Topic
Mast cells and histamine
Type
article
Field-Weighted Citation Impact
0.00
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Mast cell activation within the mesentery depends on vagal signaling following abdominal surgery

Anna Woestemeier, Sven Wehner, Timo Schwandt, Philipp Lingohr et al.
Surgery Open Science
Mast cells and histamine
article

Mast cell activation within the mesentery depends on vagal signaling following abdominal surgery

Anna Woestemeier, Sven Wehner, Timo Schwandt, Philipp Lingohr, Mariola Lysson, Gun-Soo Hong, Jörg C. Kalff
article en

Abstract

Introduction: Abdominal surgery causes an inflammatory reaction in the intestines, resulting in a postoperative ileus.Mast cells can be divided into mucosal mast cells and connective tissue mast cells.In this study, we investigated mast cell activation within the gastrointestinal tract during abdominal surgery and explored the activation and role of connective tissue mast cells in postoperative ileus.

Surgery Open ScienceVol. 31
University Hospital Bonn (DE)
Good health and well-being
Openalex Percentile: Top 11%
Mast cells and histamine
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