Clinical Safety and Healing Outcomes of an Essential-Oil Gel Versus Hyaluronic Acid: A Randomized Controlled Trial After Tooth Extraction

GelCide exhibited clinical performance and safety comparable to Gengigel, confirming that essential oils can be used safely to modulate inflammation, reduce postoperative pain, and support soft tissue healing. Essential oils constitute a safe and effective natural alternative to hyaluronic acid in postextraction wound care. Their use may be particularly suitable when a biocompatible, phytotherapeutic-based management strategy is preferred.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2026-03-23
DOI
https://doi.org/10.1097/scs.0000000000012652
Primary Topic
Dental Anxiety and Anesthesia Techniques
Type
article
Field-Weighted Citation Impact
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article

Clinical Safety and Healing Outcomes of an Essential-Oil Gel Versus Hyaluronic Acid: A Randomized Controlled Trial After Tooth Extraction

J. Carola Pérez, Javier Flores-Fraile, Luca Fiorillo, Cosimo Galletti et al.
Journal of Craniofacial Surgery
Dental Anxiety and Anesthesia Techniques
article

Clinical Safety and Healing Outcomes of an Essential-Oil Gel Versus Hyaluronic Acid: A Randomized Controlled Trial After Tooth Extraction

J. Carola Pérez, Javier Flores-Fraile, Luca Fiorillo, Cosimo Galletti, Marco Cicciù
article en

Abstract

GelCide exhibited clinical performance and safety comparable to Gengigel, confirming that essential oils can be used safely to modulate inflammation, reduce postoperative pain, and support soft tissue healing. Essential oils constitute a safe and effective natural alternative to hyaluronic acid in postextraction wound care. Their use may be particularly suitable when a biocompatible, phytotherapeutic-based management strategy is preferred.

Journal of Craniofacial Surgery
Universidad de Salamanca (ES), Università degli Studi di Enna Kore (IT), University of Catania (IT), Dr. D.Y. Patil Vidyapeeth, Pune (IN)
Openalex Percentile: Top 11%
Dental Anxiety and Anesthesia Techniques
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