Metal-Free Direct Amidation of Alkynes Using N-Boc-O-tosylhydroxylamine via Cope-type Hydroamination and Beckmann Rearrangement

The conversion of alkynes into amides has largely relied on transition-metal catalysis, whereas metal-free approaches remain scarcely explored. Herein, we report a metal-free, direct amidation of alkynes using N-Boc-O-tosylhydroxylamine (TsONHBoc)...

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Publication Details

Journal
Chemical Communications
Published
2026-01-01
DOI
https://doi.org/10.1039/d6cc01075j
Primary Topic
Chemical Synthesis and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Metal-Free Direct Amidation of Alkynes Using N-Boc-O-tosylhydroxylamine via Cope-type Hydroamination and Beckmann Rearrangement

Bal Krishna Mishra, Bhoopendra Tiwari, Ashirwad Divedi, Jawahar Lal Jat et al.
Chemical Communications
Chemical Synthesis and Analysis
article

Metal-Free Direct Amidation of Alkynes Using N-Boc-O-tosylhydroxylamine via Cope-type Hydroamination and Beckmann Rearrangement

Bal Krishna Mishra, Bhoopendra Tiwari, Ashirwad Divedi, Jawahar Lal Jat, Mohammad Amir
article en

Abstract

The conversion of alkynes into amides has largely relied on transition-metal catalysis, whereas metal-free approaches remain scarcely explored. Herein, we report a metal-free, direct amidation of alkynes using N-Boc-O-tosylhydroxylamine (TsONHBoc)...

Chemical Communications
Openalex Percentile: Top 12%
Chemical Synthesis and Analysis
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Metal-Free Direct Amidation of Alkynes Using N-Boc-O-tosylhydroxylamine via Cope-type Hydroamination and Beckmann Rearrangement — Bal Krishna Mishra, Bhoopendra Tiwari, et al. · Chemical Communications (2026) | TGRS Research Map | TGRS