Clinical Features and Outcomes of Treatment for Effusive Feline Infectious Peritonitis with GS-441524 in Seventeen Retrovirus-Positive Cats

Treatment success for retrovirus-positive cats with presumptive FIP was similar to previously reported outcomes for FIP alone. This could support current evidence of successful antiviral therapy for similar populations, if noncurrent, unstandardized protocols and unlicensed product use are considered. Additional studies are needed to determine ideal protocols for rapid resolution of FIP, good long-term survival, and limited relapse in retrovirus-positive cats, and the impact of the FeLV proviral load.

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Publication Details

Journal
Pathogens
Published
2026-03-21
DOI
https://doi.org/10.3390/pathogens15030337
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
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article

Clinical Features and Outcomes of Treatment for Effusive Feline Infectious Peritonitis with GS-441524 in Seventeen Retrovirus-Positive Cats

Rosa Negash, Nicole Jacque, Emma C. Hart, Wendy M. Novicoff et al.
Pathogens
Virus-based gene therapy research
article

Clinical Features and Outcomes of Treatment for Effusive Feline Infectious Peritonitis with GS-441524 in Seventeen Retrovirus-Positive Cats

Rosa Negash, Nicole Jacque, Emma C. Hart, Wendy M. Novicoff, JK Levy, Sarah E. Jones, Marilize Van der Walt, Samantha J. M. Evans
article en

Abstract

Treatment success for retrovirus-positive cats with presumptive FIP was similar to previously reported outcomes for FIP alone. This could support current evidence of successful antiviral therapy for similar populations, if noncurrent, unstandardized protocols and unlicensed product use are considered. Additional studies are needed to determine ideal protocols for rapid resolution of FIP, good long-term survival, and limited relapse in retrovirus-positive cats, and the impact of the FeLV proviral load.

PathogensVol. 15(3)
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US), University of Florida (US), Friends United (US), Ohio University (US), Film Independent (US), University of Virginia (US), Colorado State University (US)
Good health and well-being
Openalex Percentile: Top 12%
Virus-based gene therapy research
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