Obesity-associated gene mutations across cancer types: a pan-cancer analysis of TCGA data
These findings support a role for obesity in shaping the genomic landscape of tumors, highlighting the importance of integrating clinical parameters such as BMI into genomic studies to determine the potential impact of obesity on tumor evolution, heterogeneity, and treatment response.
Authors
- Francesco Verona (ORCID: https://orcid.org/0000-0001-6226-4624)
- Veronica Veschi (ORCID: https://orcid.org/0000-0002-6379-7366)
- Vincenzo Davide Pantina (ORCID: https://orcid.org/0000-0003-1144-0434)
- Alice Turdo (ORCID: https://orcid.org/0000-0002-6152-4903)
- Simone Di Franco (ORCID: https://orcid.org/0000-0002-6217-2161)
- Chiara Modica (ORCID: https://orcid.org/0000-0002-7000-5216)
- Rosario N. Brancaccio (ORCID: https://orcid.org/0000-0002-6374-693X)
- Miriam Gaggianesi (ORCID: https://orcid.org/0000-0002-7810-856X)
- Caterina D’Accardo (ORCID: https://orcid.org/0000-0003-1171-8678)
- Paola Bianca (ORCID: https://orcid.org/0000-0002-9172-0809)
- Matilde Todaro (ORCID: https://orcid.org/0000-0001-8686-8043)
- Gaetana Porcelli (ORCID: https://orcid.org/0000-0002-7991-407X)
- Giorgio Stassi (ORCID: https://orcid.org/0000-0002-1016-9059)
- Sebastiano Di Bella (ORCID: https://orcid.org/0000-0001-7161-303X)
- Francesco Orilio
- Cesare Morgante
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- BJC Reports
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1038/s44276-026-00214-0
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00