Molecular and immune landscape of recurrent and/or distant metastatic squamous cell carcinoma of the head and neck: an EORTC/IMMUCAN project
Our study highlights key molecular and immune differences across R/M SCCHN subgroups, identifies potential biomarkers, and suggests biological rationales for tailored therapeutic strategies.
Authors
- Sylvie Rusakiewicz (ORCID: https://orcid.org/0000-0001-5939-5690)
- Lucas Michon (ORCID: https://orcid.org/0000-0002-1839-4656)
- Henoch S. Hong (ORCID: https://orcid.org/0000-0002-3367-1738)
- A. van der Elst (ORCID: https://orcid.org/0000-0001-5816-1040)
- Loredana Martignetti (ORCID: https://orcid.org/0000-0003-1535-7515)
- Robin Liechti (ORCID: https://orcid.org/0000-0001-8351-4776)
- R. Galot
- Júlio Oliveira
- Daniel Herrero-Saboya
- Bruno Palau Fernandez (ORCID: https://orcid.org/0009-0005-7433-7516)
- P Devanand
- Marie-Sophie Robert
- Paul-Antoine Nicolas
- D. Schulz
- M. Morfouace
- Maya Persoons
- Sophie Déglise
- M. Pracht
- Paolo Bossi
- Stephanie Tissot
- Jean-Pascal Machiels
- Bernd Bodenmiller
- Céline Lefebvre
- Pierre Saintigny
- Caroline Even
- Nils Eling
Institutions
- Université Claude Bernard Lyon 1 (FR)
- European Organisation for Research and Treatment of Cancer (NL)
- SIB Swiss Institute of Bioinformatics (CH)
- Cliniques Universitaires Saint-Luc (BE)
- Humanitas University (IT)
- Merck KGaA, Darmstadt (Germany) (DE)
- Lyon College (US)
- University of Zurich (CH)
- European CanCer Organisation (BE)
- Institut Gustave Roussy (FR)
- Centre Hospitalier Universitaire Vaudois (CH)
- ETH Zurich (CH)
- Institute for Biomedical Engineering (CH)
- Centre Léon Bérard (FR)
- Centre Eugène Marquis (FR)
- IPO Porto (PT)
- Ludwig Cancer Research (CH)
- European Organisation for Research and Treatment of Cancer (BE)
- Servier (France) (FR)
- Physique des Cellules et Cancers (FR)
- Institut Curie (FR)
- University of Lausanne (CH)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-3377
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00