Effects of 635 nm Photobiomodulation on Human Gingival Fibroblast Proliferation: A Preliminary In Vitro Study
PBM at 635 nm promotes early enhancement of fibroblast growth and gap colonization in vitro, with effects most evident within the first 24 h. These findings suggest that PBM primarily stimulates cell growth rather than migration in the early phase of wound healing and support its potential as an adjunctive tool in gingival and soft tissue repair, particularly in contexts requiring a balance between cellular proliferation and migration.
Authors
- Stefano Guizzardi (ORCID: https://orcid.org/0000-0003-2395-8767)
- Maria Teresa Colangelo (ORCID: https://orcid.org/0000-0002-4664-5766)
- Roberto Sala (ORCID: https://orcid.org/0000-0002-9167-0020)
- Carlo Galli (ORCID: https://orcid.org/0000-0001-7476-7181)
- Paolo Vescovi (ORCID: https://orcid.org/0000-0002-2223-3716)
- Roberta Iaria (ORCID: https://orcid.org/0009-0009-6380-3437)
- Francesca Marti
- Marco Meleti
- Rita Antonelli
Institutions
- University of Parma (IT)
Publication Details
- Journal
- Photobiomodulation Photomedicine and Laser Surgery
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1177/25785478261434252
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00