TRENDS IN THE CLINICALPRESENTATION OF CELIAC DISEASE IN BRAZILIAN ADULTS SEEN IN THE LAST 50 YEARS IN A PRIVATE OFFICE
Over the last 50 years, the clinical presentation of CD in Southern Brazil has shifted from advanced malnourished states with diarrhea to more heterogeneous profiles including constipation and overweight. Despite advances in serology, duodenal biopsy remains the gold standard for diagnosis. These findings underscore the importance of continuous clinical vigilance and reflect a sustained contribution to CD management in Brazil.
Authors
- Luiz Roberto Kotze (ORCID: https://orcid.org/0000-0001-8456-4361)
- Lorete Maria da Silva Kotze (ORCID: https://orcid.org/0000-0003-2683-6132)
- Shirley Ramos da Rosa Utiyama
- Fabiana Antunes ANDRADE
- Renato NISIHARA
Institutions
- Universidade Federal do Paraná (BR)
- Universidade Positivo (BR)
Publication Details
- Journal
- Arquivos de Gastroenterologia
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1590/s0004-2803.24612025-118
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00