Commentary: With Regards to the WISDOM trial

Risk-based screening includes varying screening protocols for women based on their risk of breast cancer. The WISDOM trial incorporates universal genetic testing for nine susceptibility genes into risk assessment. Carriers of high-penetrance mutations are offered an annual MRI. One-third of the women with a mutation would not have qualified for genetic testing based on traditional criteria.

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Publication Details

Journal
BJC Reports
Published
2026-03-23
DOI
https://doi.org/10.1038/s44276-026-00210-4
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Commentary: With Regards to the WISDOM trial

Steven A. Narod
BJC Reports
BRCA gene mutations in cancer
article

Commentary: With Regards to the WISDOM trial

Steven A. Narod
article en

Abstract

Risk-based screening includes varying screening protocols for women based on their risk of breast cancer. The WISDOM trial incorporates universal genetic testing for nine susceptibility genes into risk assessment. Carriers of high-penetrance mutations are offered an annual MRI. One-third of the women with a mutation would not have qualified for genetic testing based on traditional criteria.

BJC ReportsVol. 4(1)
Women's College Hospital (CA)
Gender equality
Openalex Percentile: Top 12%
BRCA gene mutations in cancer
DOIOpen Access PDFOpenAlex
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