Reactive Metabolite Post-Translational Modifications: Linking Metabolism and Cellular Homeostasis

Post-translational modifications (PTMs) include the addition of functional chemical groups, representing a crucial biochemical process that occurs after or during the synthesis of proteins, considerably impacting protein function, stability, localization, and interaction. In this ToxWatch, we review reactive metabolite PTMs as presented at the Fall 2025 American Chemical Society Meeting as part of the symposium entitled: Reactive Metabolite Post-Translational Modifications and Their Analysis.

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Publication Details

Journal
Chemical Research in Toxicology
Published
2026-03-23
DOI
https://doi.org/10.1021/acs.chemrestox.5c00465
Primary Topic
Microbial Metabolic Engineering and Bioproduction
Type
article
Field-Weighted Citation Impact
0.00
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article

Reactive Metabolite Post-Translational Modifications: Linking Metabolism and Cellular Homeostasis

Reinner O. Omondi, Krishna C. Gurajala
Chemical Research in Toxicology
Microbial Metabolic Engineering and Bioproduction
article

Reactive Metabolite Post-Translational Modifications: Linking Metabolism and Cellular Homeostasis

Reinner O. Omondi, Krishna C. Gurajala
article en

Abstract

Post-translational modifications (PTMs) include the addition of functional chemical groups, representing a crucial biochemical process that occurs after or during the synthesis of proteins, considerably impacting protein function, stability, localization, and interaction. In this ToxWatch, we review reactive metabolite PTMs as presented at the Fall 2025 American Chemical Society Meeting as part of the symposium entitled: Reactive Metabolite Post-Translational Modifications and Their Analysis.

Chemical Research in Toxicology
University of Kansas (US)
Zero hunger
Openalex Percentile: Top 12%
Microbial Metabolic Engineering and Bioproduction
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