Sustainable AI-Enabled UAV Healthcare Logistics: Environmental, Social, and Governance Implications from a PRISMA-ScR Review

Artificial intelligence (AI)-enabled unmanned aerial vehicles (UAVs) are rapidly emerging as transformative technologies for sustainable healthcare logistics, particularly in remote and infrastructure-constrained regions. Despite growing implementation, the environmental, social, and governance (ESG) implications of these systems remain insufficiently synthesized in the literature. This study conducts a PRISMA-ScR-guided Systematic Review of 37 peer-reviewed studies selected from 333 records across six major scientific databases (2015–2026). The analysis reveals a sharp acceleration of research after 2021, with over 80% of publications produced between 2021 and 2024, indicating increasing global interest in AI-supported autonomous medical logistics. Evidence demonstrates that AI-enabled drones can substantially reduce delivery times; expand access to blood, vaccines, and essential medicines; and enhance emergency response capacity in rural and disaster-affected environments. From a sustainability perspective, AI-driven route optimization and autonomous navigation may reduce transport-related emissions, supporting climate-responsive healthcare supply chains. However, large-scale deployment remains constrained by regulatory fragmentation, cybersecurity risks, operational limitations, and challenges with social acceptance. This review proposes an ESG-oriented framework linking technological innovation, ethical governance, and equitable healthcare access while identifying key research gaps in lifecycle sustainability assessment, cost-effectiveness modeling, and real-world implementation aligned with the Sustainable Development Goals (SDGs).