Cysteine desulfurase protects against intracerebral hemorrhage by inhibiting neuronal ferroptosis through the suppression of iron-responsive element–binding protein 2-mediated iron-starvation responses
NFS1 may alleviate ICH damage by suppressing neuronal ferroptotic death via the downregulation of the iron-starvation response, suggesting a prospective therapeutic target for the treatment of this disorder.
Authors
- Xiaohu Wang (ORCID: https://orcid.org/0009-0005-0876-3680)
- Ye Feng (ORCID: https://orcid.org/0000-0002-6551-1560)
- Jiuhong Ma
Institutions
- Shanxi Medical University (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Neuroreport
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1097/wnr.0000000000002250
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00