Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults

We demonstrate super-additive interactions between decreases in leukocyte mtDNA<sub>CN</sub> and inflammation on the mortality risk in older adults, indicating underlying synergism.

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Publication Details

Journal
Communications Medicine
Published
2026-03-23
DOI
https://doi.org/10.1038/s43856-026-01531-8
Primary Topic
Mitochondrial Function and Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults

Ta-Tsung Lin, Pei‐Fen Chen, I -Chien Wu, Wen-Ling Cheng et al.
Communications Medicine
Mitochondrial Function and Pathology
article

Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults

Ta-Tsung Lin, Pei‐Fen Chen, I -Chien Wu, Wen-Ling Cheng, Chin-San Liu
article en

Abstract

We demonstrate super-additive interactions between decreases in leukocyte mtDNA<sub>CN</sub> and inflammation on the mortality risk in older adults, indicating underlying synergism.

Communications Medicine
National Health Research Institutes (TW), China Medical University (TW), Changhua Christian Hospital (TW)
Good health and well-being
Openalex Percentile: Top 12%
Mitochondrial Function and Pathology
DOIOpen Access PDFOpenAlex
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