VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answering

We introduce VerifAI, an open-source expert system for biomedical question answering that integrates retrieval-augmented generation (RAG) with a novel post-hoc claim verification mechanism. Unlike standard RAG systems, VerifAI ensures factual consistency by decomposing generated answers into atomic claims and validating them against retrieved evidence using a fine-tuned natural language inference (NLI) engine. The system comprises three modular components: (1) a hybrid Information Retrieval (IR) module optimized for biomedical queries (MAP@10 of 42.7%), (2) a citation-aware Generative Component fine-tuned on a custom dataset to produce referenced answers, and (3) a Verification Component that detects hallucinations with state-of-the-art accuracy, outperforming GPT-4 on the HealthVer benchmark. Evaluations demonstrate that VerifAI significantly reduces hallucinated citations compared to zero-shot baselines and provides a transparent, verifiable lineage for every claim. The full pipeline, including code, models, and datasets, is open-sourced to facilitate reliable AI deployment in high-stakes domains.

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Publication Details

Journal
IEEE Access
Published
2026-01-01
DOI
https://doi.org/10.1109/access.2026.3676985
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00
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article

VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answering

Darija Medvecki, Adela Ljajić, Nikola Milošević, Bojana Bašaragin et al.
IEEE Access
Biomedical Text Mining and Ontologies
article

VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answering

Darija Medvecki, Adela Ljajić, Nikola Milošević, Bojana Bašaragin, Lorenzo Cassano, Miloš Košprdić
article en

Abstract

We introduce VerifAI, an open-source expert system for biomedical question answering that integrates retrieval-augmented generation (RAG) with a novel post-hoc claim verification mechanism. Unlike standard RAG systems, VerifAI ensures factual consistency by decomposing generated answers into atomic claims and validating them against retrieved evidence using a fine-tuned natural language inference (NLI) engine. The system comprises three modular components: (1) a hybrid Information Retrieval (IR) module optimized for biomedical queries (MAP@10 of 42.7%), (2) a citation-aware Generative Component fine-tuned on a custom dataset to produce referenced answers, and (3) a Verification Component that detects hallucinations with state-of-the-art accuracy, outperforming GPT-4 on the HealthVer benchmark. Evaluations demonstrate that VerifAI significantly reduces hallucinated citations compared to zero-shot baselines and provides a transparent, verifiable lineage for every claim. The full pipeline, including code, models, and datasets, is open-sourced to facilitate reliable AI deployment in high-stakes domains.

IEEE AccessVol. 14
Bayer (Germany) (DE)
Openalex Percentile: Top 12%
Biomedical Text Mining and Ontologies
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VerifAI: A Verifiable Open-Source Search Engine for Biomedical Question Answering — Darija Medvecki, Adela Ljajić, et al. · IEEE Access (2026) | TGRS Research Map | TGRS