Nonenzymatic Carbamoylation and Phosphorylation via Urea Nitrosylation under Mild Aqueous Conditions

Here we present copper sulfide-promoted urea nitrosylation as a nonenzymatic means of carbamoylation, demonstrating a variety of prebiotically important reactions, including the formation of carbamoyl phosphate from urea and phosphate,...

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Publication Details

Journal
Chemical Communications
Published
2026-01-01
DOI
https://doi.org/10.1039/d5cc05999b
Primary Topic
Origins and Evolution of Life
Type
article
Field-Weighted Citation Impact
0.00
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article

Nonenzymatic Carbamoylation and Phosphorylation via Urea Nitrosylation under Mild Aqueous Conditions

Shotaro Tagawa, Norio Kitadai, Ryuhei Nakamura, Nishiki Tomizawa
Chemical Communications
Origins and Evolution of Life
article

Nonenzymatic Carbamoylation and Phosphorylation via Urea Nitrosylation under Mild Aqueous Conditions

Shotaro Tagawa, Norio Kitadai, Ryuhei Nakamura, Nishiki Tomizawa
article en

Abstract

Here we present copper sulfide-promoted urea nitrosylation as a nonenzymatic means of carbamoylation, demonstrating a variety of prebiotically important reactions, including the formation of carbamoyl phosphate from urea and phosphate,...

Chemical Communications
Clean water and sanitation
Openalex Percentile: Top 10%
Origins and Evolution of Life
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Nonenzymatic Carbamoylation and Phosphorylation via Urea Nitrosylation under Mild Aqueous Conditions — Shotaro Tagawa, Norio Kitadai, et al. · Chemical Communications (2026) | TGRS Research Map | TGRS