Validation of magnetic resonance imaging for quantification of intrapancreatic fat deposition using phantom and histologic comparators: a systematic review and meta-analysis

Question Could chemical shift-encoded magnetic resonance imaging (CSE-MRI) become the modality of choice for non-invasive quantification of intrapancreatic fat deposition? Findings Fat fraction measured by CSE-MRI closely matched known phantom values and correlated strongly with histologically determined fat in the pancreas. Clinical relevance Broad use of CSE-MRI for quantifying intrapancreatic fat deposition has the potential to reduce the global burden of pancreatitis, pancreatic cancer, and type 2 diabetes mellitus.