GPVI deficiency reduces clot size and murine thrombosis in normoglycaemic but not hyperglycemic conditions
Our data suggest that clot formation is affected differentially by absence of GPVI in normo- vs hyperglycemia, supporting a role for GPVI in thrombosis under normoglycaemic conditions only.
Authors
- KM Naseem
- Amanda D. V. MacCannell (ORCID: https://orcid.org/0000-0002-1294-5250)
- Helen R. McPherson (ORCID: https://orcid.org/0000-0002-3519-498X)
- Julia S. Gauer (ORCID: https://orcid.org/0000-0002-0835-639X)
- Lee D. Roberts (ORCID: https://orcid.org/0000-0002-1455-5248)
- Cédric Duval (ORCID: https://orcid.org/0000-0002-4870-6542)
- R Ariëns
- Ramzi A. Ajjan
Institutions
- University of Leeds (GB)
Publication Details
- Journal
- Platelets
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1080/09537104.2026.2646681
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00