An Orthogonal Extraction Workflow for High-Depth Plasma Proteomics with Metabolomic Compatibility from Low Microliter-Scale Samples

Plasma proteomics serves as the cornerstone of clinical biomarker development, yet standalone profiling is plagued by three critical bottlenecks: poor detection of low-abundance proteins, overlapping signals across pathologically similar diseases,...

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Publication Details

Journal
Analytical Methods
Published
2026-01-01
DOI
https://doi.org/10.1039/d6ay00195e
Primary Topic
Advanced Proteomics Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

An Orthogonal Extraction Workflow for High-Depth Plasma Proteomics with Metabolomic Compatibility from Low Microliter-Scale Samples

Wanjun Zhang, Xiaohong 钱小红 Qian, Chuanping Zhao, Weijie Qin et al.
Analytical Methods
Advanced Proteomics Techniques and Applications
article

An Orthogonal Extraction Workflow for High-Depth Plasma Proteomics with Metabolomic Compatibility from Low Microliter-Scale Samples

Wanjun Zhang, Xiaohong 钱小红 Qian, Chuanping Zhao, Weijie Qin, Huiting Hu
article en

Abstract

Plasma proteomics serves as the cornerstone of clinical biomarker development, yet standalone profiling is plagued by three critical bottlenecks: poor detection of low-abundance proteins, overlapping signals across pathologically similar diseases,...

Analytical Methods
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Openalex Percentile: Top 11%
Advanced Proteomics Techniques and Applications
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An Orthogonal Extraction Workflow for High-Depth Plasma Proteomics with Metabolomic Compatibility from Low Microliter-Scale Samples — Wanjun Zhang, Xiaohong 钱小红 Qian, et al. · Analytical Methods (2026) | TGRS Research Map | TGRS