Stricture classification of pediatric esophageal strictures (SCOPES): A novel tool to predict response to endoscopic therapy

The SCOPES classification tool identifies physical stricture features that significantly influence response to endoscopic therapy. Circumferential symmetry and scar tissue protuberance were associated with higher treatment burden, suggesting these characteristics may guide therapeutic decision-making. SCOPES may aid in individualizing endoscopic management of pediatric esophageal strictures and warrants prospective validation.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-03-23
DOI
https://doi.org/10.1002/jpn3.70403
Primary Topic
Esophageal and GI Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Stricture classification of pediatric esophageal strictures (SCOPES): A novel tool to predict response to endoscopic therapy

Peter Ngo, Michael A. Manfredi, Steven J. Staffa, Jessica L. Yasuda et al.
Journal of Pediatric Gastroenterology and Nutrition
Esophageal and GI Pathology
article

Stricture classification of pediatric esophageal strictures (SCOPES): A novel tool to predict response to endoscopic therapy

Peter Ngo, Michael A. Manfredi, Steven J. Staffa, Jessica L. Yasuda, Denis Chang, Brandon T. Oby
article en

Abstract

The SCOPES classification tool identifies physical stricture features that significantly influence response to endoscopic therapy. Circumferential symmetry and scar tissue protuberance were associated with higher treatment burden, suggesting these characteristics may guide therapeutic decision-making. SCOPES may aid in individualizing endoscopic management of pediatric esophageal strictures and warrants prospective validation.

Journal of Pediatric Gastroenterology and Nutrition
Boston Children's Hospital (US), Children's Hospital of Philadelphia (US), Boston Children's Museum (US), Icahn School of Medicine at Mount Sinai (US)
Peace, Justice and strong institutions
Openalex Percentile: Top 12%
Esophageal and GI Pathology
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Stricture classification of pediatric esophageal strictures (SCOPES): A novel tool to predict response to endoscopic therapy — Peter Ngo, Michael A. Manfredi, et al. · Journal of Pediatric Gastroenterology and Nutrition (2026) | TGRS Research Map | TGRS