Review of Infections in Immunocompromised Travellers: Epidemiology, Infection Prevention and Management

International travel has increased significantly in recent years. Many travellers are immunocompromised, making them more susceptible to infectious diseases due to their weakened immune systems. This narrative review provides an overview of infection epidemiology, prevention strategies, and clinical management for immunocompromised travellers. We demonstrate the role of pre-travel consultation, emphasizing individualized risk assessment informed by destination-specific epidemiology, immune status, and underlying conditions. Key preventive interventions, including vaccination strategies, antimicrobial prophylaxis, and detailed health counseling, in addition to practical measures that can be taken to minimize infection risk during travel, are addressed. Post-travel surveillance and early recognition of travel-related infections are analyzed, highlighting the importance of prompt symptom evaluation. Effective care for immunocompromised travellers requires a multidisciplinary framework that integrates patients, primary care physicians, infectious disease specialists, and travel medicine experts.