Association Between HLA Polymorphisms and Non-Alcoholic Fatty Liver Disease in Patients with Rheumatoid Arthritis: An Observational Study

In this RA cohort, metabolic factors (particularly BMI and triglycerides) were the dominant predictors of CAP-defined steatosis. No robust association between the tested HLA markers and steatosis or fibrosis was identified. Trend-level signals-most notably HLA-DRB1*15 for fibrosis-should be considered hypothesis-generating and warrant replication in larger, adequately powered cohorts.

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Publication Details

Journal
Diseases
Published
2026-03-22
DOI
https://doi.org/10.3390/diseases14030113
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between HLA Polymorphisms and Non-Alcoholic Fatty Liver Disease in Patients with Rheumatoid Arthritis: An Observational Study

Filip Blažić, Nataša Katalinić, Tatjana Zekić, Nada Starcević Cizmarević et al.
Diseases
Liver Disease Diagnosis and Treatment
article

Association Between HLA Polymorphisms and Non-Alcoholic Fatty Liver Disease in Patients with Rheumatoid Arthritis: An Observational Study

Filip Blažić, Nataša Katalinić, Tatjana Zekić, Nada Starcević Cizmarević, Aleksandar Čubranić
article en

Abstract

In this RA cohort, metabolic factors (particularly BMI and triglycerides) were the dominant predictors of CAP-defined steatosis. No robust association between the tested HLA markers and steatosis or fibrosis was identified. Trend-level signals-most notably HLA-DRB1*15 for fibrosis-should be considered hypothesis-generating and warrant replication in larger, adequately powered cohorts.

DiseasesVol. 14(3)
University of Rijeka (HR)
Good health and well-being
Openalex Percentile: Top 15%
Liver Disease Diagnosis and Treatment
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