Chemical Emulation of the Biosynthesis of (±)-Arnebidin

We report a 13-step biomimetic total synthesis of (±)-arnebidin from 1,5-dihydroxynaphthalene. An intermolecular Diels-Alder homodimerization triggers spontaneous dehydrogenation and an intramolecular cycloaddition, delivering a single diastereomer under ambient conditions. This...

Authors

Jun Deng
Zhilong Feng
Tao Zhang
Shoufeng Wang
Nan Wang

Publication Details

Journal: Chemical Communications
Published: 2026-01-01
DOI: https://doi.org/10.1039/d6cc00770h
Primary Topic: Phytochemistry and biological activities of Ficus species
Type: article
Field-Weighted Citation Impact: 0.00

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article

Chemical Emulation of the Biosynthesis of (±)-Arnebidin

Jun Deng, Zhilong Feng, Tao Zhang, Shoufeng Wang et al.

Jan 1, 2026

Chemical Communications

Phytochemistry and biological activities of Ficus species

article

Chemical Emulation of the Biosynthesis of (±)-Arnebidin

Jun Deng, Zhilong Feng, Tao Zhang, Shoufeng Wang, Nan Wang

January 1, 2026article en

Abstract

Chemical Communications

Openalex Percentile: Top 12%

Phytochemistry and biological activities of Ficus species

DOI Source OpenAlex

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Chemical Emulation of the Biosynthesis of (±)-Arnebidin — Jun Deng, Zhilong Feng, et al. · Chemical Communications (2026) | TGRS Research Map | TGRS