Egg ladder versus oral immunotherapy in infants with egg allergy: A single-center, retrospective cohort study

In this real-world cohort of infants with egg allergy, the EL approach achieved whole‑egg tolerance comparable to OIT and a substantially faster and higher tolerance to egg-containing processed foods, as expected given the EL protocol design. Although overall AE rates were similar between the approaches, no treatment‑related anaphylaxis occurred with EL, suggesting that the EL approach represents a safer and more practical strategy for dietary expansion in this age group.

Authors

Publication Details

Journal
International Archives of Allergy and Immunology
Published
2026-03-23
DOI
https://doi.org/10.1159/000551661
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Egg ladder versus oral immunotherapy in infants with egg allergy: A single-center, retrospective cohort study

Tetsuya Takamasu, Ayumi Tsukahara, Chisato Inuo, Mayumi Fujita et al.
International Archives of Allergy and Immunology
Food Allergy and Anaphylaxis Research
article

Egg ladder versus oral immunotherapy in infants with egg allergy: A single-center, retrospective cohort study

Tetsuya Takamasu, Ayumi Tsukahara, Chisato Inuo, Mayumi Fujita, Yurika Matsumoto, Yuki Ohara
article en

Abstract

In this real-world cohort of infants with egg allergy, the EL approach achieved whole‑egg tolerance comparable to OIT and a substantially faster and higher tolerance to egg-containing processed foods, as expected given the EL protocol design. Although overall AE rates were similar between the approaches, no treatment‑related anaphylaxis occurred with EL, suggesting that the EL approach represents a safer and more practical strategy for dietary expansion in this age group.

International Archives of Allergy and Immunology
Openalex Percentile: Top 10%
Food Allergy and Anaphylaxis Research
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