Association between short-term radiation-induced toxicity and oncological outcomes in high-risk prostate cancer: a retrospective single-centre cohort study
Early grade ≥ 2 GU-toxicity was linked to worse FFBR and MFS after EBRT alone, whereas no such association was seen after EBRT-BT. GI toxicity showed no prognostic impact. These exploratory findings warrant validation in larger studies addressing interactions between patient-, tumour- and treatment-related factors.
Authors
- Henrik Ugge (ORCID: https://orcid.org/0000-0002-0098-5300)
- Bengt Johansson (ORCID: https://orcid.org/0000-0002-0163-5062)
- Jenny Kahlmeter Brandell
- A. Valachis
- Daniel Smith
Institutions
- Örebro University (SE)
- Örebro University Hospital (SE)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2026-03-23
- DOI
- https://doi.org/10.2340/1651-226x.2026.45030
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00