Autologous stem cell transplant for severe, progressive juvenile systemic sclerosis
Juvenile systemic sclerosis (jSSc) is a rare, chronic, autoimmune disease in children/adolescents and is associated with significant morbidity, skin thickening/hardening (scleroderma), organ toxicity and sub-optimal therapeutic options. In this report, autologous stem cell transplantation is associated with clinical improvement in a 17-year-old with refractory jSSc.
Authors
- Shaikha Alqahtani (ORCID: https://orcid.org/0009-0004-1176-8952)
- Fabiana Cacace (ORCID: https://orcid.org/0009-0006-8788-8461)
- Kris Michael Mahadeo (ORCID: https://orcid.org/0000-0003-2649-9674)
- Andrea Bauchat
- Nicole Larrier
- Brittany Paige DePriest
- Timothy A. Driscoll
- Jeffery Dvergsten
- Carmem Bonfim
- Joanne Kurtzberg
Institutions
- Duke University (US)
- Santobono Children's Hospital (IT)
- Duke University Hospital (US)
Publication Details
- Journal
- Stem Cells Translational Medicine
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1093/stcltm/szag005
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00