Correlation between single-nucleotide polymorphisms at the rs3745453 locus of the miR-23a gene and sudden sensorineural hearing loss in the Han population

These findings suggest that miR-23a expression levels may serve as an independent diagnostic biomarker for SSNHL, while the miR-23a expression and rs3745453 polymorphism are associated with increased susceptibility to adult-onset SSNHL.

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Publication Details

Journal
Neurological Research
Published
2026-03-22
DOI
https://doi.org/10.1080/01616412.2026.2637835
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
Field-Weighted Citation Impact
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article

Correlation between single-nucleotide polymorphisms at the rs3745453 locus of the miR-23a gene and sudden sensorineural hearing loss in the Han population

Rui Da, Yang Wang, Peng Chen
Neurological Research
Hearing, Cochlea, Tinnitus, Genetics
article

Correlation between single-nucleotide polymorphisms at the rs3745453 locus of the miR-23a gene and sudden sensorineural hearing loss in the Han population

Rui Da, Yang Wang, Peng Chen
article en

Abstract

These findings suggest that miR-23a expression levels may serve as an independent diagnostic biomarker for SSNHL, while the miR-23a expression and rs3745453 polymorphism are associated with increased susceptibility to adult-onset SSNHL.

Neurological Research
Jiangsu University (CN), Universidad Rey Juan Carlos (ES), Kunming Children's Hospital (CN), Affiliated Hospital of Jiangsu University (CN), Women’s Health Care (US)
Good health and well-being
Openalex Percentile: Top 10%
Hearing, Cochlea, Tinnitus, Genetics
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