Effect of ondansetron on QTc interval prolongation in healthy pediatric patients: a systematic review and meta-analysis
There was a statistically significant increase in QTc and Tp-e intervals following ondansetron administration in healthy pediatric patients. However, it is highly unlikely that these changes result in cardiac dysrhythmia, suggesting no relationship between low-dose ondansetron use and an increased risk of dysrhythmia in healthy pediatric patients.
Authors
- Paulo Eduardo Souza Castelo Branco (ORCID: https://orcid.org/0000-0001-8077-1187)
- Isabela Maurício Costa Carneiro
- Amanda Prates de Oliveira (ORCID: https://orcid.org/0009-0006-1094-9342)
- Adriane Helena Silva Franco (ORCID: https://orcid.org/0000-0003-0497-872X)
- Agatha Marcela Andrade de Aguiar
Institutions
- Faculdade Brasil (BR)
Publication Details
- Journal
- Revista Paulista de Pediatria
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1590/1984-0462/2026/44/2025134
- Primary Topic
- Nausea and vomiting management
- Type
- article
- Field-Weighted Citation Impact
- 0.00