Biomaterial used to counteract ridge reduction following the removal of adjacent teeth: A randomized controlled multicenter study

When 2 neighboring teeth are removed, the area tends to shrink in width and height as it heals. This bone loss can make it more difficult to place dental implants later. In this study, we tested a method to help maintain the bone after removing 2 adjacent teeth. In the Test group, the empty tooth sockets were filled with a bone graft material (deproteinized bovine bone mineral and collagen) and covered with a collagen membrane. In the Control group, the sites were left to heal physiologically. A total of 42 patients participated, each needing 2 side-by-side teeth removed. After 6 months of healing, we compared models of the patients from right after the extractions to those taken 6 months later. The results showed that the group with the bone graft and membrane had much less bone shrinkage than the group without them. The 2 extraction sites in the graft group maintained their bone height and width similarly. In summary, using a bone substitute material and membrane immediately after multiple tooth extractions helped preserve the jawbone, which could make future treatments like dental implants more successful.

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Publication Details

Journal
Journal of Periodontology
Published
2026-03-23
DOI
https://doi.org/10.1002/jper.70084
Primary Topic
Dental Implant Techniques and Outcomes
Type
article
Field-Weighted Citation Impact
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article

Biomaterial used to counteract ridge reduction following the removal of adjacent teeth: A randomized controlled multicenter study

Enrico Savio, Marco Toia, Denis Cecchinato, M. Gervasi et al.
Journal of Periodontology
Dental Implant Techniques and Outcomes
article

Biomaterial used to counteract ridge reduction following the removal of adjacent teeth: A randomized controlled multicenter study

Enrico Savio, Marco Toia, Denis Cecchinato, M. Gervasi, Marco Menoncin, Enrico Corrà, Eriberto Bressan
article en

Abstract

When 2 neighboring teeth are removed, the area tends to shrink in width and height as it heals. This bone loss can make it more difficult to place dental implants later. In this study, we tested a method to help maintain the bone after removing 2 adjacent teeth. In the Test group, the empty tooth sockets were filled with a bone graft material (deproteinized bovine bone mineral and collagen) and covered with a collagen membrane. In the Control group, the sites were left to heal physiologically. A total of 42 patients participated, each needing 2 side-by-side teeth removed. After 6 months of healing, we compared models of the patients from right after the extractions to those taken 6 months later. The results showed that the group with the bone graft and membrane had much less bone shrinkage than the group without them. The 2 extraction sites in the graft group maintained their bone height and width similarly. In summary, using a bone substitute material and membrane immediately after multiple tooth extractions helped preserve the jawbone, which could make future treatments like dental implants more successful.

Journal of Periodontology
University of Padua (IT), Malmö University (SE), Ospedale Maggiore (IT), Institute of Ionized Gas (IT)
Openalex Percentile: Top 12%
Dental Implant Techniques and Outcomes
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Biomaterial used to counteract ridge reduction following the removal of adjacent teeth: A randomized controlled multicenter study — Enrico Savio, Marco Toia, et al. · Journal of Periodontology (2026) | TGRS Research Map | TGRS