Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer

Automated quantification of BPE from DCE-MRI provides an objective and reproducible imaging biomarker associated with treatment response and overall survival in breast cancer. These results support its potential utility for individualized risk stratification and therapeutic decision-making.

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Publication Details

Journal
Breast Cancer Research and Treatment
Published
2026-03-24
DOI
https://doi.org/10.1007/s10549-026-07941-5
Primary Topic
MRI in cancer diagnosis
Type
article
Field-Weighted Citation Impact
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article

Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer

Siddarth Ragupathi, Chris Chung, Ha Manh Luu, Yihui Zhu et al.
Breast Cancer Research and Treatment
MRI in cancer diagnosis
article

Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer

Siddarth Ragupathi, Chris Chung, Ha Manh Luu, Yihui Zhu, Jeremy Weiss, Wei Hou, Takouhie Maldjian, Tim Q. Duong, Surya Hariharan, Hien Quang Nguyen, Roham Hadidchi
article en

Abstract

Automated quantification of BPE from DCE-MRI provides an objective and reproducible imaging biomarker associated with treatment response and overall survival in breast cancer. These results support its potential utility for individualized risk stratification and therapeutic decision-making.

Breast Cancer Research and TreatmentVol. 216(3)
Albert Einstein College of Medicine (US), Montefiore Health System (US), VNU University of Science (VN), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 14%
MRI in cancer diagnosis
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Automated calculation of background parenchymal enhancement as a biomarker of treatment responses and recurrence-free survival in breast cancer — Siddarth Ragupathi, Chris Chung, et al. · Breast Cancer Research and Treatment (2026) | TGRS Research Map | TGRS