Statement on education and scientific research in the field of therapeutic drug monitoring by the COST Action ENOTTA CA21147

The present article discusses and highlights the need for education and scientific research in the field of therapeutic drug monitoring (TDM) through the prism of the COST Action on the European Network on Optimising Treatment with Therapeutic Antibodies in Chronic Inflammatory Diseases (ENOTTA). The overall hypothesis was that training schools and short-term scientific missions (STSM) would advance the field in areas with a high need for knowledge exchange. Educational and research topics span the spectrum of the manufacturing of biological and personalized medicines, quality assurance, clinical research, regulatory approval, treatment evaluation, predicting therapeutic results via modeling, stratification of patients, assay of biologicals concentration in plasma, and cost-effectiveness of therapeutic drug monitoring. In conclusion, we put forward that an educational program on TDM may be helpful in advancing the field and should include the aforementioned subjects. In addition, clinical application and interpretation in a variety of treatment areas should be presented in detail. Such a comprehensive educational program will respond to the requirements of best practices in TDM and future developments in the area.