Elucidating the phase 1 trial experience among study participants following completion of the INTERCEPT-AD study of sabirnetug (ACU193) for early Alzheimer’s disease: a qualitative interview study

Study findings suggest opportunities to enhance the AD trial experience by addressing trial-related burdens and logistical aspects of participation. Exploratory gender analyses yielded additional insight into the patient trial experience but should be further examined along with race/ethnicity and study partner characteristics to enhance clinical study design and execution.

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Publication Details

Journal
Trials
Published
2026-03-23
DOI
https://doi.org/10.1186/s13063-026-09656-w
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Elucidating the phase 1 trial experience among study participants following completion of the INTERCEPT-AD study of sabirnetug (ACU193) for early Alzheimer’s disease: a qualitative interview study

Carrie Presnall, Stephanie Cline, Elizabeth Merikle, Eric Siemers et al.
Trials
Dementia and Cognitive Impairment Research
article

Elucidating the phase 1 trial experience among study participants following completion of the INTERCEPT-AD study of sabirnetug (ACU193) for early Alzheimer’s disease: a qualitative interview study

Carrie Presnall, Stephanie Cline, Elizabeth Merikle, Eric Siemers, Diana Kerwin, Robyn Moxon, Todd Feaster
article en

Abstract

Study findings suggest opportunities to enhance the AD trial experience by addressing trial-related burdens and logistical aspects of participation. Exploratory gender analyses yielded additional insight into the patient trial experience but should be further examined along with race/ethnicity and study partner characteristics to enhance clinical study design and execution.

Trials
Outcomes Research Consortium (US), St. Mary-Corwin Medical Center (US), Film Independent (US), Acumen Pharmaceuticals (United States) (US)
Openalex Percentile: Top 22%
Dementia and Cognitive Impairment Research
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