Diagnosis of penile cancer with <i>ex vivo</i> fluorescence confocal microscopy using the Histolog® Scanner

Ex vivo FCM is a feasible, rapid imaging technique that enables high concordance with histopathology for the diagnosis of PeCa. This pilot study represents the first assessment of ex vivo FCM in penile malignancies and provides preliminary evidence supporting its potential role in intraoperative margin assessment. Larger prospective studies are required to confirm its diagnostic accuracy and clinical utility.

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Publication Details

Journal
British Journal of Urology
Published
2026-03-23
DOI
https://doi.org/10.1111/bju.70239
Primary Topic
Genital Health and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

Larissa Mendes, Hussain M. Alnajjar, Asif Muneer, Alex Freeman et al.
British Journal of Urology
Genital Health and Disease
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Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

Larissa Mendes, Hussain M. Alnajjar, Asif Muneer, Alex Freeman, Xiaohu Zhang, Greg Shaw, Aiman Haider, Daniela Fleck Lavergne, Ricardo Almeida‐Magana
article en

Abstract

Ex vivo FCM is a feasible, rapid imaging technique that enables high concordance with histopathology for the diagnosis of PeCa. This pilot study represents the first assessment of ex vivo FCM in penile malignancies and provides preliminary evidence supporting its potential role in intraoperative margin assessment. Larger prospective studies are required to confirm its diagnostic accuracy and clinical utility.

British Journal of Urology
University College London Hospitals NHS Foundation Trust (GB), UCL Biomedical Research Centre (GB), University College London (GB)
Openalex Percentile: Top 13%
Genital Health and Disease
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