High-dose vs standard-dose vitamin D and sleep in early childhood: A randomized clinical trial

We observed that high-dose versus standard-dose vitamin D<sub>3</sub> provides no benefits for child's sleep, even if we found an association between child's higher 25(OH)D and less sleep disturbances. Higher maternal 25(OH)D during pregnancy was associated with child's better sleep, which should be studied further.

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Publication Details

Journal
Sleep Medicine
Published
2026-03-23
DOI
https://doi.org/10.1016/j.sleep.2026.108913
Primary Topic
Vitamin D Research Studies
Type
article
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0.00
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article

High-dose vs standard-dose vitamin D and sleep in early childhood: A randomized clinical trial

Maria Enlund-Cerullo, Samuel Sandboge, Jenni Rosendahl, Saara Valkama et al.
Sleep Medicine
Vitamin D Research Studies
article

High-dose vs standard-dose vitamin D and sleep in early childhood: A randomized clinical trial

Maria Enlund-Cerullo, Samuel Sandboge, Jenni Rosendahl, Saara Valkama, Vilja Seppälä, Kati Heinonen, Elisa Holmlund-Suila, Helena Hauta-alus, Katri Räikkönen, Eero Kajantie, Sture Andersson, Outi Mäkitie
article en

Abstract

We observed that high-dose versus standard-dose vitamin D<sub>3</sub> provides no benefits for child's sleep, even if we found an association between child's higher 25(OH)D and less sleep disturbances. Higher maternal 25(OH)D during pregnancy was associated with child's better sleep, which should be studied further.

Sleep MedicineVol. 143
Karolinska University Hospital (SE), University of Helsinki (FI), Oulu University Hospital (FI), Helsinki University Hospital (FI), Helsinki Children's Hospital (FI), Tampere University (FI), Institute for Molecular Medicine Finland (FI), University of Oulu (FI)
Zero hunger
Openalex Percentile: Top 14%
Vitamin D Research Studies
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High-dose vs standard-dose vitamin D and sleep in early childhood: A randomized clinical trial — Maria Enlund-Cerullo, Samuel Sandboge, et al. · Sleep Medicine (2026) | TGRS Research Map | TGRS