Leishmania infantum in red foxes (Vulpes vulpes): from clinical findings to cytokine expression

The present study confirmed a high L. infantum prevalence of infection in red foxes from southern Italy. Serological findings herein and in the literature, together with in vitro cytokine gene expression, suggested that most foxes may remain subclinically infected. The high molecular positivity and the synanthropic nature of red foxes reinforce their role as reservoirs of L. infantum in endemic areas.

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Publication Details

Journal
Parasites & Vectors
Published
2026-03-23
DOI
https://doi.org/10.1186/s13071-026-07334-z
Primary Topic
Research on Leishmaniasis Studies
Type
article
Field-Weighted Citation Impact
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article

Leishmania infantum in red foxes (Vulpes vulpes): from clinical findings to cytokine expression

Floriana Gernone, Viviane Noll Louzada-Flores, Antonio Camarda, Michela Prioletti et al.
Parasites & Vectors
Research on Leishmaniasis Studies
article

Leishmania infantum in red foxes (Vulpes vulpes): from clinical findings to cytokine expression

Floriana Gernone, Viviane Noll Louzada-Flores, Antonio Camarda, Michela Prioletti, Natalizia Palazzo, Mario Alves, Filipe Dantas-Torres, Jairo Alfonso Mendoza-Roldan, Domenico Otranto, Mariaelisa Carbonara, Marcos Antonio Bezerra-Santos
article en

Abstract

The present study confirmed a high L. infantum prevalence of infection in red foxes from southern Italy. Serological findings herein and in the literature, together with in vitro cytokine gene expression, suggested that most foxes may remain subclinically infected. The high molecular positivity and the synanthropic nature of red foxes reinforce their role as reservoirs of L. infantum in endemic areas.

Parasites & Vectors
Inserm (FR), Institut Pasteur (FR), City University of Hong Kong (HK), Université Paris Cité (FR), University of Pavia (IT), Fundação Oswaldo Cruz (BR), University of Bari Aldo Moro (IT)
Responsible consumption and production
Openalex Percentile: Top 15%
Research on Leishmaniasis Studies
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