Back to the flow: a comprehensive systematic review and meta-analysis of epinephrine in the treatment of no-reflow

Therefore, intracoronary epinephrine was associated with encouraging but exploratory findings, and the higher success rate in primary no-reflow may reflect earlier intervention and less severe microvascular damage. Its modest advantage over adenosine suggests potential therapeutic value, though evidence remains limited and heterogeneous.

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Publication Details

Journal
Coronary Artery Disease
Published
2026-03-23
DOI
https://doi.org/10.1097/mca.0000000000001632
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Back to the flow: a comprehensive systematic review and meta-analysis of epinephrine in the treatment of no-reflow

F Ribeiro, L. M. da SILVA, Gabriel Rezende Neves, Kalgi Modi et al.
Coronary Artery Disease
Coronary Interventions and Diagnostics
article

Back to the flow: a comprehensive systematic review and meta-analysis of epinephrine in the treatment of no-reflow

F Ribeiro, L. M. da SILVA, Gabriel Rezende Neves, Kalgi Modi, Guilherme Sobreira Spina, Pedro Antônio Machado Gomes de Sousa, Leonardo Galvão de Oliveira Oldra, P Antonio Machado Gomes De Sousa, C Farias, Eduarda Dexheimer da Silva, Ricardo Fonseca Oliveira Suruagy-Motta, Miguel Rodrigues Moreira, Leonardo Cadorin de Araújo, Kauã Gabriel Oliveira
article en

Abstract

Therefore, intracoronary epinephrine was associated with encouraging but exploratory findings, and the higher success rate in primary no-reflow may reflect earlier intervention and less severe microvascular damage. Its modest advantage over adenosine suggests potential therapeutic value, though evidence remains limited and heterogeneous.

Coronary Artery Disease
Universidade de São Paulo (BR), Anhembi Morumbi University (BR), Universidade do Estado do Pará (BR), Louisiana State University in Shreveport (US), Universidade Nove de Julho (BR), Universidade Federal de Santa Maria (BR), Centro Universitário Cesmac (BR), Universidade Federal de Uberlândia (BR), Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 13%
Coronary Interventions and Diagnostics
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Back to the flow: a comprehensive systematic review and meta-analysis of epinephrine in the treatment of no-reflow — F Ribeiro, L. M. da SILVA, et al. · Coronary Artery Disease (2026) | TGRS Research Map | TGRS