Mechanisms underlying the protective effects of San‐Bai decoction against <scp>UV</scp> radiation on the skin
USBT2627 suppresses melanin accumulation in vitro and protects skin against UV exposure in both in vitro and in vivo models; multiple components, targets and pathways of SBD act together to confer its protective effect against UV exposure. These findings highlight a significant potential of topical USBT2627 in protecting skin against UV exposure. Additionally, this study showcases the value of a systems network approach in elucidating the mechanisms of this herbal blend, offering valuable references for further research aimed at developing TCM-based products.
Authors
- H. Zhang
- Yimei Tan (ORCID: https://orcid.org/0000-0003-3688-7435)
- Luonan Chen
- Wencai Jiang
- Ying Zou
- Xuelan Gu
- Chengming Zhang
- Rui Zhang
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Sciences (CN)
- National Medical Products Administration (CN)
- Unilever (China) (CN)
- Center for Excellence in Molecular Cell Science (CN)
- Shanghai Skin Disease Hospital (CN)
- The University of Tokyo (JP)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1111/ics.70093
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00