A phantom study to achieve comparable 124I PET recovery and address scanner variability for dosimetry purposes in (re)differentiated thyroid cancer
Vendor-recommended <sup>124</sup>I acquisition and reconstruction leads to differences in quantification but can be compensated using a bias correction. Recovery correction is minimally affected by different BG-to-lesion ratios, suggesting that one RC curve is sufficient, simplifying <sup>124</sup>I calibration procedures in studies requiring <sup>124</sup>I quantification.
Authors
- Dennis Vriens (ORCID: https://orcid.org/0000-0001-5762-6766)
- Mette K. Stam (ORCID: https://orcid.org/0009-0004-2843-1854)
- Maaike Dotinga (ORCID: https://orcid.org/0000-0002-8384-7164)
- Prof Lioe-Fee de Geus-Oei
- Lenka M. Pereira Arias-Bouda
- Floris H.P. van Velden
- Petra Dibbets-Schneider
- Ellen Kapiteijn
- Martin Pool
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- Oncode Institute (NL)
- Delft University of Technology (NL)
Publication Details
- Journal
- Physica Medica
- Published
- 2026-03-23
- DOI
- https://doi.org/10.1016/j.ejmp.2026.105772
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00